Objective : Tetragonia tetragonioides(Tt) has been used for injlammatory disease, skin disease and some kind of cancer in folk remedy. In order to investigate the effect of anti-oxidation of Tt, this study was done.
Methods : Tt was investigated effects of antioxidation for DPPH(electron donating ability) radical ability, nitrate reductase(NR) activity, superoxide dismutase(SOD) activity, catalase activity, lipid peroxidase(LP) and glutathione(GSH).
Results : In vitro, DPPH radical ability and nitrate reductase activity(NR) were significantly increased to the level of BHT. In vivo, compared with normal group, SOD activity and catalase activity were decreased in the acetaminophen treated group. On the other hand, Tt in the pretreated groups SOD activity and catalase activity were significantly increased. Compared with normal group, LP was increased in acetaminophen treated group. On the other hand, Tt in the pretreated groups were decreased. In the acetaminophen treated group, GSH activity was decreased by compare with normal group. And in the Tt pretreated groups, GSH activity was increased to the control group.
Conclusion : According to the above results, the antioxidant anction of Tetragonia tetragonioides(Tt) is effective. And it is expected to be necessary to the study of the mechanism in the antioxidant of Tt.
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